ASB2 Antibody
| Code | Size | Price |
|---|
| PSI-59-067-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Ankyrin repeat and SOCS box protein 2, ASB-2, ASB2
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is a member of the
ankyrin repeat and SOCS box-containing (ASB) family of proteins.
They contain ankyrin repeat sequence and SOCS box domain. The SOCS
box serves to couple suppressor of cytokine signalling (SOCS)
proteins and their binding partners with the elongin B and C
complex, possibly targeting them for degradation. This gene is
induced by all-trans retinoic acid. In myeloid leukemia cells, the
expression of this encoded protein has been shown to induce growth
inhibition and chromatin condensation. Multiple alternatively
spliced transcript variants have been described for this gene but
their full length sequences are not known.
Background References:
- Heuze, M.L., et al. Blood 112(13):5130-5140(2008)
- Kohroki, J., et al. FEBS Lett. 579(30):6796-6802(2005)
- Heuze, M.L., et al. J. Biol. Chem. 280(7):5468-5474(2005)
- Colland, F., et al. Genome Res. 14(7):1324-1332(2004)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This ASB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 58-86 amino acids from the N-terminal region of human ASB2.
NCBI Gene ID #:
51676
NCBI Official Name:
Ankyrin repeat and SOCS box protein 2
NCBI Official Symbol:
ASB2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
65 kDa
Protein Accession #:
Q96Q27
Protein GI Number:
20531999
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
Q96Q27
User NOte:
Optimal dilutions for each application to be determined by the researcher.