GSDMB Antibody

ProSci
Product Code: PSI-63-516
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-63-516-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis of GSDMB Antibody in HL-60, MDA-MB435 cell line lysates (35ug/lane)

Western blot analysis of GSDMB Antibody in HL-60, MDA-MB435 cell line lysates (35ug/lane)

Further Information

Additional Names:
Gasdermin-B, Gasdermin-like protein, GSDMB, GSDML
Application Note:
For WB starting dilution is: 1:1000
Background:
GSDMB is a protein with 3' exonuclease activity. Enzymes with this activity are involved in DNA replication, repair, and recombination. Similarity to an E. coli protein suggests that this enzyme may be a subunit of DNA polymerase III, which does not have intrinsic exonuclease activity.
Background References:
  • Hur,J.W., et.al., Rheumatol. Int. 28 (8), 783-789 (2008)
  • Chen,M.J., et.al., Nucleic Acids Res. 35 (8), 2682-2694 (2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This GSDMB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 208-237 amino acids from the Central region of human GSDMB.
NCBI Gene ID #:
55876
NCBI Official Name:
Gasdermin-B
NCBI Official Symbol:
GSDMB
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
47 kDa
Protein Accession #:
Q8TAX9
Protein GI Number:
182647404
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
Q8TAX9
User NOte:
Optimal dilutions for each application to be determined by the researcher.