EIF4G2 Antibody

ProSci
Product Code: PSI-61-051
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-61-051-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis of lysate from K562 cell line, using EIF4G2 Antibody at 1:1000.

Western blot analysis of lysate from K562 cell line, using EIF4G2 Antibody at 1:1000.

Further Information

Additional Names:
Eukaryotic translation initiation factor 4 gamma 2, eIF-4-gamma 2, eIF-4G 2, eIF4G 2, Death-associated protein 5, DAP-5, p97, EIF4G2 (HGNC:3297)
Application Note:
For WB starting dilution is: 1:1000
Background:
Appears to play a role in the switch from cap-dependent to IRES-mediated translation during mitosis, apoptosis and viral infection. Cleaved by some caspases and viral proteases.
Background References:
  • Imataka H.,et al.EMBO J. 16:817-825(1997).
  • Yamanaka S.,et al.Genes Dev. 11:321-333(1997).
  • Levy-Strumpf N.,et al.Mol. Cell. Biol. 17:1615-1625(1997).
  • Totoki Y.,et al.Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rabbit
Immunogen:
This EIF4G2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 12-44 amino acids from the N-terminal region of human EIF4G2.
NCBI Gene ID #:
1982
NCBI Official Name:
Eukaryotic translation initiation factor 4 gamma 2
NCBI Official Symbol:
EIF4G2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
102 kDa
Protein Accession #:
P78344
Protein GI Number:
30315906
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
P78344
User NOte:
Optimal dilutions for each application to be determined by the researcher.