ALG2 Antibody
| Code | Size | Price |
|---|
| PSI-59-049-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Alpha-1,3/1,6-mannosyltransferase ALG2, Asparagine-linked glycosylation protein 2 homolog, GDP-Man:Man(1)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase, GDP-Man:Man(1)GlcNAc(2)-PP-dolichol mannosyltransferase, GDP-Man:Man(2)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase, ALG2
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a member of the glycosyltransferase 1
family. The encoded protein acts as an alpha 1,3
mannosyltransferase, mannosylating Man(2)GlcNAc(2)-dolichol
diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form
Man(3)GlcNAc(2)-dolichol diphosphate. Defects in this gene have
been associated with congenital disorder of glycosylation type Ih
(CDG-Ii). Alternative splicing results in multiple transcript
variants.
Background References:
- Inuzuka, T., et al. BMC Struct. Biol. 10, 25 (2010) :
- Okumura, M., et al. Biochem. Biophys. Res. Commun. 386(1):237-241(2009)
- Hoj, B.R., et al. Biochem. Biophys. Res. Commun. 378(1):145-148(2009)
- Mahul-Mellier, A.L., et al. J. Biol. Chem. 283(50):34954-34965(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This ALG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 254-282 amino acids from the Central region of human ALG2.
NCBI Gene ID #:
85365
NCBI Official Name:
Alpha-1,3/1,6-mannosyltransferase ALG2
NCBI Official Symbol:
ALG2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
47 kDa
Protein Accession #:
Q9H553
Protein GI Number:
46395991
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
Q9H553
User NOte:
Optimal dilutions for each application to be determined by the researcher.