PSG4 Antibody

ProSci
Product Code: PSI-60-276
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-60-276-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in MDA-MB453 cell line lysates (35ug/lane).

Western blot analysis in MDA-MB453 cell line lysates (35ug/lane).

Further Information

Additional Names:
Pregnancy-specific beta-1-glycoprotein 4, PS-beta-G-4, PSBG-4, Pregnancy-specific glycoprotein 4, Pregnancy-specific beta-1-glycoprotein 9, PS-beta-G-9, PSBG-9, Pregnancy-specific glycoprotein 9, PSG4, CGM4, PSG9
Application Note:
For WB starting dilution is: 1:1000
Background:
The human pregnancy-specific glycoproteins (PSGs) are a family of proteins that are synthesized in large amounts by placental trophoblasts and released into the maternal circulation during pregnancy. Molecular cloning and analysis of several PSG genes has indicated that the PSGs form a subgroup of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily of genes. Members of the CEA family consist of a single N domain, with structural similarity to the immunoglobulin variable domains, followed by a variable number of immunoglobulin constant-like A and/or B domains. Most PSGs have an arg-gly-asp (RGD) motif, which has been shown to function as an adhesion recognition signal for several integrins, in the N-terminal domain (summary by Teglund et al., 1994 [PubMed 7851896]). For additional general information about the PSG gene family, see PSG1 (MIM 176390).
Background References:
  • Kimoto, Y. Mol. Gen. Genet. 258(3):233-239(1998)
  • Teglund, S., et al. Biochem. Biophys. Res. Commun. 211(2):656-664(1995)
  • Teglund, S., et al. Genomics 23(3):669-684(1994)
  • Olsen, A., et al. Genomics 23(3):659-668(1994)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PSG4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 73-100 amino acids from the N-terminal region of human PSG4.
NCBI Gene ID #:
5672
NCBI Official Name:
Pregnancy-specific beta-1-glycoprotein 4
NCBI Official Symbol:
PSG4
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
47 kDa
Protein Accession #:
Q00888
Protein GI Number:
313104197
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
Q00888
User NOte:
Optimal dilutions for each application to be determined by the researcher.