UBP46 Antibody
| Code | Size | Price |
|---|
| PSI-57-525-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Ubiquitin carboxyl-terminal hydrolase 46, Deubiquitinating enzyme 46, Ubiquitin thioesterase 46, Ubiquitin-specific-processing protease 46, USP46
Application Note:
For WB starting dilution is: 1:1000
Background:
Modification of cellular proteins by ubiquitin is an
essential regulatory mechanism controlled by the coordinated action
of multiple ubiquitin-conjugating and deubiquitinating enzymes.
USP46 belongs to a large family of cysteine proteases that function
as deubiquitinating enzymes (Quesada et al., 2004 [PubMed
14715245]).
Background References:
- Kushima, I., et al. J. Hum. Genet. 55(3):133-136(2010)
- Cohn, M.A., et al. J. Biol. Chem. 284(8):5343-5351(2009)
- Zemunik, T., et al. Croat. Med. J. 50(1):23-33(2009)
- Quesada, V., et al. Biochem. Biophys. Res. Commun. 314(1):54-62(2004)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Zebrafish, Mouse
Immunogen:
This UBP46 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 241-269 amino acids from the C-terminal region of human UBP46.
NCBI Gene ID #:
64854
NCBI Official Name:
Ubiquitin carboxyl-terminal hydrolase 46
NCBI Official Symbol:
USP46
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
42 kDa
Protein Accession #:
P62068
Protein GI Number:
49065850
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
P62068
User NOte:
Optimal dilutions for each application to be determined by the researcher.