UBE2H Antibody
| Code | Size | Price |
|---|
| PSI-58-808-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Ubiquitin-conjugating enzyme E2 H, UbcH2, Ubiquitin carrier protein H, Ubiquitin-conjugating enzyme E2-20K, Ubiquitin-protein ligase H, UBE2H
Application Note:
For WB starting dilution is: 1:1000
Background:
The modification of proteins with ubiquitin is an
important cellular mechanism for targeting abnormal or short-lived
proteins for degradation. Ubiquitination involves at least three
classes of enzymes: ubiquitin-activating enzymes, or E1s,
ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein
ligases, or E3s. This gene encodes a member of the E2
ubiquitin-conjugating enzyme family. The encoded protein sequence
is 100% identical to the mouse homolog and 98% identical to the
frog and zebrafish homologs. Two alternatively spliced transcript
variants have been found for this gene and they encode distinct
isoforms.
Background References:
- Lausen, J., et al. J. Biol. Chem. 285(8):5338-5346(2010)
- Martin, I., et al. Amyotroph Lateral Scler 10 (5-6), 432-435 (2009) :
- de Krom, M., et al. Biol. Psychiatry 65(7):625-630(2009)
- Martin, I., et al. Amyotroph Lateral Scler, 1-4 (2008) In press :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse
Immunogen:
This UBE2H antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 42-70 amino acids from the Central region of human UBE2H.
NCBI Gene ID #:
7328
NCBI Official Name:
Ubiquitin-conjugating enzyme E2 H
NCBI Official Symbol:
UBE2H
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
21 kDa
Protein Accession #:
P62256
Protein GI Number:
51338683
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
P62256
User NOte:
Optimal dilutions for each application to be determined by the researcher.