FBXO5 Antibody
| Code | Size | Price |
|---|
| PSI-58-707-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
F-box only protein 5, Early mitotic inhibitor 1, FBXO5, EMI1, FBX5
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a member of the F-box protein family
which is characterized by an approximately 40 amino acid motif, the
F-box. The F-box proteins constitute one of the four subunits of
the ubiquitin protein ligase complex called SCFs
(SKP1-cullin-F-box), which function in phosphorylation-dependent
ubiquitination. The F-box proteins are divided into 3 classes: Fbws
containing WD-40 domains, Fbls containing leucine-rich repeats, and
Fbxs containing either different protein-protein interaction
modules or no recognizable motifs. The protein encoded by this gene
belongs to the Fbxs class. This protein is similar to xenopus early
mitotic inhibitor-1 (Emi1), which is a mitotic regulator that
interacts with Cdc20 and inhibits the anaphase promoting complex.
Alternatively spliced transcript variants encoding different
isoforms have been identified.
Background References:
- Lei, S.F., et al. J. Bone Miner. Res. (2010) In press :
- Ma, H.T., et al. Mol. Cell. Biol. 29(24):6500-6514(2009)
- Lee, J., et al. Mol. Biol. Cell 20(7):1891-1902(2009)
- Gutgemann, I., et al. Mod. Pathol. 21(4):445-454(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This FBXO5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 192-221 amino acids from the Central region of human FBXO5.
NCBI Gene ID #:
26271
NCBI Official Name:
F-box only protein 5
NCBI Official Symbol:
FBXO5
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
50 kDa
Protein Accession #:
Q9UKT4
Protein GI Number:
24636847
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
Q9UKT4
User NOte:
Optimal dilutions for each application to be determined by the researcher.