TFAP2B Antibody
| Code | Size | Price |
|---|
| PSI-56-956-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Transcription factor AP-2-beta, AP2-beta, Activating enhancer-binding protein 2-beta, TFAP2B
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a member of the AP-2 family of
transcription factors. AP-2 proteins form homo- or hetero-dimers
with other AP-2 family members and bind specific DNA sequences.
They are thought to stimulate cell proliferation and suppress
terminal differentiation of specific cell types during embryonic
development. Specific AP-2 family members differ in their
expression patterns and binding affinity for different promoters.
This protein functions as both a transcriptional activator and
repressor. Mutations in this gene result in autosomal dominant Char
syndrome, suggesting that this gene functions in the
differentiation of neural crest cell derivatives. [provided by
RefSeq].
Background References:
- Li, X., et al. Genes Chromosomes Cancer 49(9):819-830(2010)
- Hotta, K., et al. J. Hum. Genet. (2010) In press :
- Ugi, S., et al. Obesity (Silver Spring) 18(7):1277-1282(2010)
- Nordquist, N., et al. Brain Res. 1305 SUPPL, S20-S26 (2009) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This TFAP2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 431-462 amino acids from the C-terminal region of human TFAP2B.
NCBI Gene ID #:
7021
NCBI Official Name:
Transcription factor AP-2-beta
NCBI Official Symbol:
TFAP2B
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
50 kDa
Protein Accession #:
Q92481
Protein GI Number:
152031557
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
Q92481
User NOte:
Optimal dilutions for each application to be determined by the researcher.