SERPINI2 Antibody
Code | Size | Price |
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PSI-59-363-400ul | 400ul | £626.00 |
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Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Serpin I2, Myoepithelium-derived serine protease inhibitor, Pancpin, Pancreas-specific protein TSA2004, Peptidase inhibitor 14, PI-14, SERPINI2, MEPI, PI14
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is a member of the serine
protease inhibitor (serpin) superfamily made up of proteins which
play central roles in the regulation of a wide variety of
physiological processes, including coagulation, fibrinolysis,
development, malignancy and inflammation. The gene product may have
a role in a growth-control, possibly growth-suppressing pathway
and, when impaired, may be involved in pancreatic carcinogenesis.
The protein is a member of the plasminogen activator inhibitor-1
family, a subset of the serpin superfamily whose members act as
tissue-specific tPA inhibitors. Two alternatively spliced
transcript variants encoding distinct protein isoforms have been
found for this gene.
Background References:
- Liu, C.Y., et al. Carcinogenesis 31(7):1259-1263(2010)
- Lim, J., et al. Cell 125(4):801-814(2006)
- Chang, W.S., et al. Genes Chromosomes Cancer 29(3):240-255(2000)
- Xiao, G., et al. Proc. Natl. Acad. Sci. U.S.A. 96(7):3700-3705(1999)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This SERPINI2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 375-401 amino acids from the C-terminal region of human SERPINI2.
NCBI Gene ID #:
5276
NCBI Official Name:
Serpin I2
NCBI Official Symbol:
SERPINI2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
46 kDa
Protein Accession #:
O75830
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
O75830
User NOte:
Optimal dilutions for each application to be determined by the researcher.