MPPE1 Antibody

ProSci
Product Code: PSI-59-985
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-59-985-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in NCI-H292 cell line lysates (35ug/lane).

Western blot analysis in NCI-H292 cell line lysates (35ug/lane).

Further Information

Additional Names:
Metallophosphoesterase 1, 31--, Post-GPI attachment to proteins factor 5, MPPE1, PGAP5
Application Note:
For WB starting dilution is: 1:1000
Background:
Metallophosphoesterase required for transport of GPI-anchor proteins from the endoplasmic reticulum to the Golgi. Acts in lipid remodeling steps of GPI-anchor maturation by mediating the removal of a side-chain ethanolamine-phosphate (EtNP) from the second Man (Man2) of the GPI intermediate, an essential step for efficient transport of GPI-anchor proteins.
Background References:
  • Lohoff, F.W., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 153B (3), 830-836 (2010) :
  • Fujita, M., et al. Cell 139(2):352-365(2009)
  • Yosifova, A., et al.Affect Disord 117 (1-2), 87-97 (2009) :
  • Fortna, A., et al. PLoS Biol.(7), E207 (2004) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Monkey
Immunogen:
This MPPE1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 261-289 amino acids from the C-terminal region of human MPPE1.
NCBI Gene ID #:
65258
NCBI Official Name:
Metallophosphoesterase 1
NCBI Official Symbol:
MPPE1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
45 kDa
Protein Accession #:
Q53F39
Protein GI Number:
215274110
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
Q53F39
User NOte:
Optimal dilutions for each application to be determined by the researcher.