MRC2 Antibody

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ProSci
Product Code: PSI-58-238
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-58-238-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in NCI-H460 cell line lysates (35ug/lane).
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Western blot analysis in NCI-H460 cell line lysates (35ug/lane).

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Further Information

Additional Names:
C-type mannose receptor 2, C-type lectin domain family 13 member E, Endocytic receptor 180, Macrophage mannose receptor 2, Urokinase-type plasminogen activator receptor-associated protein, UPAR-associated protein, Urokinase receptor-associated protein, CD280, MRC2, CLEC13E, ENDO180, KIAA0709, UPARAP
Application Note:
For WB starting dilution is: 1:1000
Background:
MRC2 is a recycling endocytic receptor that functions in cell motility and remodeling of the extracellular matrix by promoting cell migration and uptake of collagens for intracellular degradation (Wienke et al., 2007 [PubMed 17974964]).[supplied by OMIM].
Background References:
  • Messaritou, G., et al. J. Cell. Sci. 122 (PT 22), 4042-4048 (2009) :
  • Wu, X., et al. Cancer Prev Res (Phila Pa) 2(7):617-624(2009)
  • Wienke, D., et al. Cancer Res. 67(21):10230-10240(2007)
  • Sulek, J., et al. J. Histochem. Cytochem. 55(4):347-353(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This MRC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 798-827 amino acids from the Central region of human MRC2.
NCBI Gene ID #:
9902
NCBI Official Name:
C-type mannose receptor 2
NCBI Official Symbol:
MRC2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
167 kDa
Protein Accession #:
Q9UBG0
Protein GI Number:
317373394
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
Q9UBG0
User NOte:
Optimal dilutions for each application to be determined by the researcher.