CRISP1 Antibody
| Code | Size | Price |
|---|
| PSI-59-344-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Cysteine-rich secretory protein 1, CRISP-1, AEG-like protein, ARP, Acidic epididymal glycoprotein homolog, CRISP1, AEGL1
Application Note:
For WB starting dilution is: 1:1000
Background:
Fertilization consists of a sequence of specific cell-cell
interactions culminating in the fusion of the sperm and egg plasma
membranes. Recognition, binding, and fusion occur through the
interaction of complementary molecules that are localized to
specific domains of the sperm and egg plasma membranes. In the
sperm, the postacrosomal region or equatorial segment is involved
in sperm-egg plasma membrane fusion. The protein encoded by this
gene is a member of the cysteine-rich secretory protein (CRISP)
family. This protein is expressed in the epididymis, is secreted
into the epididymal lumen, and binds to the postacrosomal region of
the sperm head where it plays a role at fertilization in sperm-egg
fusion through complementary sites localized on the egg surface.
Two isoforms are encoded by transcript variants of this gene.
Background References:
- Mungall, A.J., et al. Nature 425(6960):805-811(2003)
- Evans, J.P. Hum. Reprod. Update 8(4):297-311(2002)
- Cuasnicu, P.S., et al. Arch. Med. Res. 32(6):614-618(2001)
- Cohen, D.J., et al. Biol. Reprod. 65(4):1000-1005(2001)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CRISP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 162-191 amino acids from the C-terminal region of human CRISP1.
NCBI Gene ID #:
167
NCBI Official Name:
Cysteine-rich secretory protein 1
NCBI Official Symbol:
CRISP1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
28 kDa
Protein Accession #:
P54107
Protein GI Number:
1706134
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
P54107
User NOte:
Optimal dilutions for each application to be determined by the researcher.