CHTF18 Antibody

ProSci
Product Code: PSI-56-780
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-56-780-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

1 / 1
Western blot analysis in NCI-H292 cell line lysates (35ug/lane).

Western blot analysis in NCI-H292 cell line lysates (35ug/lane).

Further Information

Additional Names:
Chromosome transmission fidelity protein 18 homolog, hCTF18, CHL12, CHTF18, C16orf41, CTF18
Application Note:
For WB starting dilution is: 1:1000
Background:
CHTF18, CHTF8 (MIM 613202), and DCC1 (DSCC1; MIM 613203) are components of an alternative replication factor C (RFC) (see MIM 600404) complex that loads PCNA (MIM 176740) onto DNA during S phase of the cell cycle (Merkle et al., 2003 [PubMed 12766176]; Bermudez et al., 2003 [PubMed 12930902]).
Background References:
  • Murakami, T., et al. J. Biol. Chem. 285(45):34608-34615(2010)
  • Farina, A., et al. J. Biol. Chem. 283(30):20925-20936(2008)
  • Shiomi, Y., et al. J. Biol. Chem. 282(29):20906-20914(2007)
  • Matsuoka, S., et al. Science 316(5828):1160-1166(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CHTF18 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 914-943 amino acids from the C-terminal region of human CHTF18.
NCBI Gene ID #:
63922
NCBI Official Name:
Chromosome transmission fidelity protein 18 homolog
NCBI Official Symbol:
CHTF18
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
107 kDa
Protein Accession #:
Q8WVB6
Protein GI Number:
74751544
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
Q8WVB6
User NOte:
Optimal dilutions for each application to be determined by the researcher.