DCC1 Antibody
Code | Size | Price |
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PSI-61-568-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Sister chromatid cohesion protein DCC1, Defective in sister chromatid cohesion protein 1 homolog, DSCC1, DCC1
Application Note:
For WB starting dilution is: 1:1000
Background:
CHTF18 (MIM 613201), CHTF8 (MIM 613202), and DSCC1 are
components of an alternative replication factor C (RFC) (see MIM
600404) complex that loads PCNA (MIM 176740) onto DNA during S
phase of the cell cycle (Merkle et al., 2003 [PubMed 12766176];
Bermudez et al., 2003 [PubMed 12930902]).
Background References:
- Murakami, T., et al. J. Biol. Chem. 285(45):34608-34615(2010)
- Terret, M.E., et al. Nature 462(7270):231-234(2009)
- Watrin, E., et al. Curr. Biol. 16(9):863-874(2006)
- Bermudez, V.P., et al. Proc. Natl. Acad. Sci. U.S.A. 100(18):10237-10242(2003)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This DCC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 311-339 amino acids from the C-terminal region of human DCC1.
NCBI Gene ID #:
79075
NCBI Official Name:
Sister chromatid cohesion protein DCC1
NCBI Official Symbol:
DSCC1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
45 kDa
Protein Accession #:
Q9BVC3
Protein GI Number:
167012058
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
Q9BVC3
User NOte:
Optimal dilutions for each application to be determined by the researcher.