YTHD2 Antibody
| Code | Size | Price |
|---|
| PSI-58-440-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
YTH domain-containing family protein 2, CLL-associated antigen KW-14, High-glucose-regulated protein 8, Renal carcinoma antigen NY-REN-2, YTHDF2, HGRG8
Application Note:
For WB starting dilution is: 1:1000
Background:
YTHDF2 is a member of the YTH (YT521-B homology)
superfamily containing YTH domain. The YTH domain is typical for
the eukaryotes and is particularly abundant in plants. The YTH
domain is usually located in the middle of the protein sequence and
may function in binding to RNA. In addition to a YTH domain, this
protein has a proline rich region which may be involved in signal
transduction. An Alu-rich domain has been identified in one of the
introns of this gene, which is thought to be associated with human
longevity. In addition, reciprocal translocations between this gene
and the Runx1 (AML1) gene on chromosme 21 has been observed in
patients with acute myeloid leukemia. This gene was initially
mapped to chromosome 14, which was later turned out to be a
pseudogene.
Background References:
- Nguyen, T.T., et al. Genes Chromosomes Cancer 45(10):918-932(2006)
- Cardelli, M., et al. J. Gerontol.Biol. Sci. Med. Sci. 61(6):547-556(2006)
- Rush, J., et al. Nat. Biotechnol. 23(1):94-101(2005)
- Stoilov, P., et al. Trends Biochem. Sci. 27(10):495-497(2002)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Monkey, Mouse
Immunogen:
This YTHD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 551-579 amino acids from the C-terminal region of human YTHD2.
NCBI Gene ID #:
51441
NCBI Official Name:
YTH domain-containing family protein 2
NCBI Official Symbol:
YTHDF2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
62 kDa
Protein Accession #:
Q9Y5A9
Protein GI Number:
41019527
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
Q9Y5A9
User NOte:
Optimal dilutions for each application to be determined by the researcher.