WDR45 Antibody

ProSci
Product Code: PSI-56-982
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-56-982-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western Blot at 1:1000 dilution + human heart lysate Lysates/proteins at 20 ug per lane.

Western Blot at 1:1000 dilution + human heart lysate Lysates/proteins at 20 ug per lane.

Further Information

Additional Names:
WD repeat domain phosphoinositide-interacting protein 4, WIPI-4, WD repeat-containing protein 45, WDR45, WDRX1, WDRXI4, WIPI4
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene has a pseudogene at chromosome 4q31.3. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity and full-length nature of some variants have not been determined.
Background References:
  • Proikas-Cezanne, T., et al. Oncogene 23(58):9314-9325(2004)
  • Jeffries, T.R., et al. Mol. Biol. Cell 15(6):2652-2663(2004)
  • Clark, A.G., et al. Science 302(5652):1960-1963(2003)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Zebrafish, Mouse, Rat
Immunogen:
This WDR45 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-46 amino acids from the N-terminal region of human WDR45.
NCBI Gene ID #:
11152
NCBI Official Name:
WD repeat domain phosphoinositide-interacting protein 4
NCBI Official Symbol:
WDR45
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
40 kDa
Protein Accession #:
Q9Y484
Protein GI Number:
74762056
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
Q9Y484
User NOte:
Optimal dilutions for each application to be determined by the researcher.