ALG11 Antibody
| Code | Size | Price |
|---|
| PSI-58-064-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase, Asparagine-linked glycosylation protein 11 homolog, Glycolipid 2-alpha-mannosyltransferase, ALG11, GT8
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a
GDP-Man:Man3GlcNAc2-PP-dolichol-alpha1,2-mannosyltransferase which
is localized to the cytosolic side of the endoplasmic reticulum
(ER) and catalyzes the transfer of the fourth and fifth mannose
residue from GDP-mannose (GDP-Man) to Man3GlcNAc2-PP-dolichol and
Man4GlcNAc2-PP-dolichol resulting in the production of
Man5GlcNAc2-PP-dolichol. Mutations in this gene are associated with
congenital disorder of glycosylation type Ip (CDGIP). This gene
overlaps but is distinct from the UTP14, U3 small nucleolar
ribonucleoprotein, homolog C (yeast) gene. A pseudogene of the
GDP-Man:Man3GlcNAc2-PP-dolichol-alpha1,2-mannosyltransferase has
been identified on chromosome 19.
Background References:
- Rind, N., et al. Hum. Mol. Genet. 19(8):1413-1424(2010)
- Rohozinski, J., et al. Biol. Reprod. 74(4):644-651(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This ALG11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 344-373 amino acids from the C-terminal region of human ALG11.
NCBI Gene ID #:
440138
NCBI Official Name:
GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase
NCBI Official Symbol:
ALG11
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
56 kDa
Protein Accession #:
Q2TAA5
Protein GI Number:
156631015
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
Q2TAA5
User NOte:
Optimal dilutions for each application to be determined by the researcher.