MND1 Antibody

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ProSci
Product Code: PSI-59-642
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-59-642-400ul400ul£626.00
Quantity:
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Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in HepG2 cell line lysates (35ug/lane).
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Western blot analysis in HepG2 cell line lysates (35ug/lane).

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Further Information

Additional Names:
Meiotic nuclear division protein 1 homolog, MND1 {ECO:0000312|EMBL:EAX049641}
Application Note:
For WB starting dilution is: 1:1000
Background:
The product of the MND1 gene associates with HOP2 (MIM 608665) to form a stable heterodimeric complex that binds DNA and stimulates the recombinase activity of RAD51 (MIM 179617) and DMC1 (MIM 602721) (Chi et al., 2007 [PubMed 17639080]). Both the MND1 and HOP2 genes are indispensable for meiotic recombination.
Background References:
  • Rose, J. Phd, et al. Mol. Med. (2010) In press :
  • Chi, P., et al. Genes Dev. 21(14):1747-1757(2007)
  • Enomoto, R., et al. J. Biol. Chem. 281(9):5575-5581(2006)
  • Tsubouchi, H., et al. Mol. Cell. Biol. 22(9):3078-3088(2002)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This MND1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 174-200 amino acids from the C-terminal region of human MND1.
NCBI Gene ID #:
84057
NCBI Official Name:
Meiotic nuclear division protein 1 homolog
NCBI Official Symbol:
MND1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
24 kDa
Protein Accession #:
Q9BWT6
Protein GI Number:
74733462
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
Q9BWT6
User NOte:
Optimal dilutions for each application to be determined by the researcher.