FBXL13 Antibody

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ProSci
Product Code: PSI-58-961
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-58-961-400ul400ul£626.00
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Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in NCI-H460 cell line lysates (35ug/lane).
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Western blot analysis in NCI-H460 cell line lysates (35ug/lane).

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Further Information

Additional Names:
F-box/LRR-repeat protein 13, F-box and leucine-rich repeat protein 13, FBXL13, FBL13
Application Note:
For WB starting dilution is: 1:1000
Background:
Members of the F-box protein family, such as FBXL13, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM].
Background References:
  • Rose, J. Phd, et al. Mol. Med. (2010) In press :
  • Curtiss, N.P., et al. Genomics 85(5):600-607(2005)
  • Jin, J., et al. Genes Dev. 18(21):2573-2580(2004)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This FBXL13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 683-710 amino acids from the C-terminal region of human FBXL13.
NCBI Gene ID #:
222235
NCBI Official Name:
F-box/LRR-repeat protein 13
NCBI Official Symbol:
FBXL13
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
84 kDa
Protein Accession #:
Q8NEE6
Protein GI Number:
311033450
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
Q8NEE6
User NOte:
Optimal dilutions for each application to be determined by the researcher.