DPH2 Antibody
| Code | Size | Price |
|---|
| PSI-59-759-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Diphthamide biosynthesis protein 2, DPH2 homolog, HsDph2, Diphthamide biosynthesis protein 2 homolog-like 2, DPH2-like 2, DPH2, DPH2L2
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene is one of two human genes similar to the yeast
gene dph2. The yeast gene was identified by its ability to
complement a diphthamide mutant strain, and thus probably functions
in diphthamide biosynthesis. Diphthamide is a post-translationally
modified histidine residue present in elongation factor 2 (EF2)
that is the target of diphtheria toxin ADP-ribosylation. Two
transcript variants encoding different isoforms have been found for
this gene.
Background References:
- Rose, J. Phd, et al. Mol. Med. (2010) In press :
- Liu, S., et al. Mol. Cell. Biol. 24(21):9487-9497(2004)
- Schultz, D.C., et al. Genomics 52(2):186-191(1998)
- Foley, B.T., et al. J. Biol. Chem. 270(39):23218-23225(1995)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This DPH2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 121-148 amino acids from the N-terminal region of human DPH2.
NCBI Gene ID #:
1802
NCBI Official Name:
Diphthamide biosynthesis protein 2
NCBI Official Symbol:
DPH2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
52 kDa
Protein Accession #:
Q9BQC3
Protein GI Number:
74761201
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
Q9BQC3
User NOte:
Optimal dilutions for each application to be determined by the researcher.