TP53BP2 Antibody
| Code | Size | Price |
|---|
| PSI-58-427-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Apoptosis-stimulating of p53 protein 2, Bcl2-binding protein, Bbp, Renal carcinoma antigen NY-REN-51, Tumor suppressor p53-binding protein 2, 53BP2, p53-binding protein 2, p53BP2, TP53BP2, ASPP2, BBP
Application Note:
For WB starting dilution is: 1:1000
Background:
TP53BP2 is a member of the ASPP
(apoptosis-stimulating protein of p53) family of p53 interacting
proteins. The protein contains four ankyrin repeats and an SH3
domain involved in protein-protein interactions. It is localized to
the perinuclear region of the cytoplasm, and regulates apoptosis
and cell growth through interactions with other regulatory
molecules including members of the p53 family. Multiple transcript
variants encoding different isoforms have been found for this gene.
Background References:
- Rose, J. Phd, et al. Mol. Med. (2010) In press :
- Zhao, J., et al. Hepatology 51(1):142-153(2010)
- Hirata, H., et al. J. Urol. 182(2):721-727(2009)
- Kweekel, D.M., et al. Br. J. Cancer 101(2):357-362(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This TP53BP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 93-122 amino acids from the N-terminal region of human TP53BP2.
NCBI Gene ID #:
7159
NCBI Official Name:
Apoptosis-stimulating of p53 protein 2
NCBI Official Symbol:
TP53BP2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
126 kDa
Protein Accession #:
Q13625
Protein GI Number:
33860140
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
Q13625
User NOte:
Optimal dilutions for each application to be determined by the researcher.