LMBR1 Antibody
| Code | Size | Price |
|---|
| PSI-59-097-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Limb region 1 protein homolog, Differentiation-related gene 14 protein, LMBR1, C7orf2, DIF14
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a member of the LMBR1-like membrane
protein family. Another member of this protein family has been
shown to be a lipocalin transmembrane receptor. A highly conserved,
cis-acting regulatory module for the sonic hedgehog gene is located
within an intron of this gene. Consequently, disruption of this
genic region can alter sonic hedgehog expression and affect limb
patterning, but it is not known if this gene functions directly in
limb development. Mutations and chromosomal deletions and
rearrangements in this genic region are associated with acheiropody
and preaxial polydactyly, which likely result from altered sonic
hedgehog expression.
Background References:
- Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
- Farooq, M., et al. Eur. J. Hum. Genet. 18(6):733-736(2010)
- Rutsch, F., et al. Nat. Genet. 41(2):234-239(2009)
- He, F., et al. PLoS ONE(8), E2948 (2008) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This LMBR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 262-290 amino acids from the Central region of human LMBR1.
NCBI Gene ID #:
64327
NCBI Official Name:
Limb region 1 protein homolog
NCBI Official Symbol:
LMBR1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
55 kDa
Protein Accession #:
Q8WVP7
Protein GI Number:
74730878
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
Q8WVP7
User NOte:
Optimal dilutions for each application to be determined by the researcher.