CDC14A Antibody
| Code | Size | Price |
|---|
| PSI-59-028-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Dual specificity protein phosphatase CDC14A, CDC14 cell division cycle 14 homolog A, CDC14A
Application Note:
For WB starting dilution is: 1:1000
Background:
The protein encoded by this gene is a member of the dual
specificity protein tyrosine phosphatase family. It is highly
similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine
phosphatase involved in the exit of cell mitosis and initiation of
DNA replication, suggesting a role in cell cycle control. This
protein has been shown to interact with, and dephosphorylate tumor
suppressor protein p53, and is thought to regulate the function of
p53. Alternative splicing of this gene results in several
transcript variants encoding distinct isoforms. [provided by
RefSeq].
Background References:
- Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
- Olson, J.E., et al. Breast Cancer Res. Treat. (2010) In press :
- Mocciaro, A., et al. J. Cell Biol. 189(4):631-639(2010)
- Song, S.Y., et al. APMIS 118(5):389-393(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CDC14A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 473-500 amino acids from the C-terminal region of human CDC14A.
NCBI Gene ID #:
8556
NCBI Official Name:
Dual specificity protein phosphatase CDC14A
NCBI Official Symbol:
CDC14A
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
67 kDa
Protein Accession #:
Q9UNH5
Protein GI Number:
55976620
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
Q9UNH5
User NOte:
Optimal dilutions for each application to be determined by the researcher.