UBE2R2 Antibody
| Code | Size | Price |
|---|
| PSI-60-700-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Ubiquitin-conjugating enzyme E2 R2, Ubiquitin carrier protein R2, Ubiquitin-conjugating enzyme E2-CDC34B, Ubiquitin-protein ligase R2, UBE2R2, CDC34B, UBC3B
Application Note:
For WB starting dilution is: 1:1000
Background:
Protein kinase CK2 is a ubiquitous and pleiotropic Ser/Thr
protein kinase involved in cell growth and transformation. This
gene encodes a protein similar to the E2 ubiquitin conjugating
enzyme UBC3/CDC34. Studies suggest that CK2-dependent
phosphorylation of this ubiquitin-conjugating enzyme functions by
regulating beta-TrCP substrate recognition and induces its
interaction with beta-TrCP, enhancing beta-catenin degradation.
Background References:
- Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
- Yoshida, T., et al. Int. J. Mol. Med. 25(4):649-656(2010)
- Oguri, M., et al. Am. J. Hypertens. 23(1):70-77(2010)
- Ferreira, M.A., et al. Nat. Genet. 40(9):1056-1058(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rabbit
Immunogen:
This UBE2R2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 141-169 amino acids from the Central region of human UBE2R2.
NCBI Gene ID #:
54926
NCBI Official Name:
Ubiquitin-conjugating enzyme E2 R2
NCBI Official Symbol:
UBE2R2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
27 kDa
Protein Accession #:
Q712K3
Protein GI Number:
74749761
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
Q712K3
User NOte:
Optimal dilutions for each application to be determined by the researcher.