ABP1 Antibody

ProSci
Product Code: PSI-57-365
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-57-365-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in K562 cell line lysates (35ug/lane).

Western blot analysis in K562 cell line lysates (35ug/lane).

Further Information

Additional Names:
Amiloride-sensitive amine oxidase [copper-containing], DAO, Diamine oxidase, Amiloride-binding protein 1, Amine oxidase copper domain-containing protein 1, Histaminase, Kidney amine oxidase, KAO, AOC1, ABP1, DAO1
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a membrane glycoprotein that is expressed in many epithelium-rich and/or hematopoietic tissues and oxidatively deaminates putrescine and histamine. The protein may play a role in controlling the level of histamine and/or putrescine in these tissues. It also binds to and is inhibited by amiloride, a diuretic that acts by closing epithelial sodium ion channels.
Background References:
  • Ruano, G., et al. Pharmacogenomics 11(7):959-971(2010)
  • McGrath, A.P., et al. Acta Crystallogr. Sect.Struct. Biol. Cryst. Commun. 66 (PT 2), 137-142 (2010) :
  • Chambers, J.C., et al. Nat. Genet. 42(2):149-152(2010)
  • McGrath, A.P., et al. Biochemistry 48(41):9810-9822(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This ABP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 71-100 amino acids from the N-terminal region of human ABP1.
NCBI Gene ID #:
26
NCBI Official Name:
Amiloride-sensitive amine oxidase [copper-containing]
NCBI Official Symbol:
AOC1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
85 kDa
Protein Accession #:
P19801
Protein GI Number:
251757489
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
P19801
User NOte:
Optimal dilutions for each application to be determined by the researcher.