CCNG2 Antibody
| Code | Size | Price |
|---|
| PSI-58-656-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Cyclin-G2, CCNG2
Application Note:
For WB starting dilution is: 1:1000
Background:
The eukaryotic cell cycle is governed by cyclin-dependent
protein kinases (CDKs) whose activities are regulated by cyclins
and CDK inhibitors. The 8 species of cyclins reported in mammals,
cyclins A through H, share a conserved amino acid sequence of about
90 residues called the cyclin box. The amino acid sequence of
cyclin G is well conserved among mammals. The nucleotide sequence
of cyclin G1 and cyclin G2 are 53% identical. Unlike cyclin G1,
cyclin G2 contains a C-terminal PEST protein destabilization motif,
suggesting that cyclin G2 expression is tightly regulated through
the cell cycle.
Background References:
- Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)
- Choi, M.G., et al. J. Surg. Res. 157(2):168-174(2009)
- Cunningham, J.M., et al. Br. J. Cancer 101(8):1461-1468(2009)
- Xu, G., et al. Mol. Biol. Cell 19(11):4968-4979(2008)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This CCNG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 215-243 amino acids from the Central region of human CCNG2.
NCBI Gene ID #:
901
NCBI Official Name:
Cyclin-G2
NCBI Official Symbol:
CCNG2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
39 kDa
Protein Accession #:
Q16589
Protein GI Number:
9087132
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
Q16589
User NOte:
Optimal dilutions for each application to be determined by the researcher.