MAD1L1 Antibody
| Code | Size | Price |
|---|
| PSI-56-363-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Mitotic spindle assembly checkpoint protein MAD1, Mitotic arrest deficient 1-like protein 1, MAD1-like protein 1, Mitotic checkpoint MAD1 protein homolog, HsMAD1, hMAD1, Tax-binding protein 181, MAD1L1, MAD1, TXBP181
Application Note:
For WB starting dilution is: 1:1000
Background:
MAD1L1 is a component of the mitotic spindle-assembly
checkpoint that prevents the onset of anaphase until all chromosome
are properly aligned at the metaphase plate. MAD1L1 functions as a
homodimer and interacts with MAD2L1. MAD1L1 may play a role in cell
cycle control and tumor suppression. Three transcript variants
encoding the same protein have been found for this gene. [provided
by RefSeq].
Background References:
- Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)
- Guo, Y., et al. J. Med. Genet. 47(9):616-622(2010)
- Wang, H.B., et al. J. Gastrointest. Surg. 14(8):1227-1234(2010)
- Hewitt, L., et al. J. Cell Biol. 190(1):25-34(2010)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This MAD1L1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 124-151 amino acids from the N-terminal region of human MAD1L1.
NCBI Gene ID #:
8379
NCBI Official Name:
Mitotic spindle assembly checkpoint protein MAD1
NCBI Official Symbol:
MAD1L1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
83 kDa
Protein Accession #:
Q9Y6D9
Protein GI Number:
52783153
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
Q9Y6D9
User NOte:
Optimal dilutions for each application to be determined by the researcher.