DEDD Antibody
| Code | Size | Price |
|---|
| PSI-59-960-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Death effector domain-containing protein, DEDPro1, Death effector domain-containing testicular molecule, FLDED-1, DEDD, DEDPRO1, DEFT
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes a protein that contains a death effector
domain (DED). DED is a protein-protein interaction domain shared by
adaptors, regulators and executors of the programmed cell death
pathway. Overexpression of this gene was shown to induce weak
apoptosis. Upon stimulation, this protein was found to translocate
from cytoplasm to nucleus and colocalize with UBTF, a basal factor
required for RNA polymerase I transcription, in the nucleolus. At
least three transcript variants encoding the same protein have been
found for this gene.
Background References:
- Thorenoor, N., et al. Biochemistry 49(7):1435-1447(2010)
- Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
- Park, M.Y., et al. Int. J. Cancer 115(3):412-418(2005)
- Alcivar, A., et al. Oncogene 22(2):291-297(2003)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen:
This DEDD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 165-191 amino acids from the Central region of human DEDD.
NCBI Gene ID #:
9191
NCBI Official Name:
Death effector domain-containing protein
NCBI Official Symbol:
DEDD
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
37 kDa
Protein Accession #:
O75618
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
O75618
User NOte:
Optimal dilutions for each application to be determined by the researcher.