PSG2 Antibody
| Code | Size | Price |
|---|
| PSI-58-793-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Pregnancy-specific beta-1-glycoprotein 2, PS-beta-G-2, PSBG-2, Pregnancy-specific glycoprotein 2, Pregnancy-specific beta-1 glycoprotein E, PS-beta-E, PSG2, PSBG2
Application Note:
For WB starting dilution is: 1:1000
Background:
The human pregnancy-specific glycoproteins (PSGs) are a
family of proteins that are synthesized in large amounts by
placental trophoblasts and released into the maternal circulation
during pregnancy. Molecular cloning and analysis of several PSG
genes has indicated that the PSGs form a subgroup of the
carcinoembryonic antigen (CEA) gene family, which belongs to the
immunoglobulin superfamily of genes. Members of the CEA family
consist of a single N domain, with structural similarity to the
immunoglobulin variable domains, followed by a variable number of
immunoglobulin constant-like A and/or B domains. Most PSGs have an
arg-gly-asp (RGD) motif, which has been shown to function as an
adhesion recognition signal for several integrins, in the
N-terminal domain (summary by Teglund et al., 1994 [PubMed
7851896]). For additional general information about the PSG gene
family, see PSG1 (MIM 176390).
Background References:
- Tsavaris, N., et al.Chemother 21(6):673-680(2009)
- Mennuni, C., et al. Int. J. Cancer 117(3):444-455(2005)
- Colland, F., et al. Genome Res. 14(7):1324-1332(2004)
- Grimwood, J., et al. Nature 428(6982):529-535(2004)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PSG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 225-254 amino acids from the C-terminal region of human PSG2.
NCBI Gene ID #:
5670
NCBI Official Name:
Pregnancy-specific beta-1-glycoprotein 2
NCBI Official Symbol:
PSG2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
37 kDa
Protein Accession #:
P11465
Protein GI Number:
108935879
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
P11465
User NOte:
Optimal dilutions for each application to be determined by the researcher.