TSEN2 Antibody

ProSci
Product Code: PSI-60-318
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-60-318-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in Hela cell line lysates (35ug/lane).

Western blot analysis in Hela cell line lysates (35ug/lane).

Further Information

Additional Names:
tRNA-splicing endonuclease subunit Sen2, tRNA-intron endonuclease Sen2, HsSen2, TSEN2, SEN2
Application Note:
For WB starting dilution is: 1:1000
Background:
This gene encodes one of the subunits of the tRNA splicing endonuclease. This endonuclease catalyzes the first step in RNA splicing which is the removal of introns. Mutations in this gene have been associated with pontocerebellar hypoplasia type 2. A pseudogene has been identified on chromosome 4. Multiple transcript variants encoding different isoforms have been found for this gene.
Background References:
  • Weitzer, S., et al. Nature 447(7141):222-226(2007)
  • Lamesch, P., et al. Genomics 89(3):307-315(2007)
  • Ballif, B.A., et al. Mol. Cell Proteomics 3(11):1093-1101(2004)
  • Paushkin, S.V., et al. Cell 117(3):311-321(2004)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This TSEN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 16-43 amino acids from the N-terminal region of human TSEN2.
NCBI Gene ID #:
80746
NCBI Official Name:
tRNA-splicing endonuclease subunit Sen2
NCBI Official Symbol:
TSEN2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
53 kDa
Protein Accession #:
Q8NCE0
Protein GI Number:
50428914
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
Q8NCE0
User NOte:
Optimal dilutions for each application to be determined by the researcher.