SENP5 Antibody
| Code | Size | Price |
|---|
| PSI-57-708-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Sentrin-specific protease 5, Sentrin/SUMO-specific protease SENP5, SENP5
Application Note:
For WB starting dilution is: 1:1000
Background:
The reversible posttranslational modification of proteins
by the addition of small ubiquitin-like SUMO proteins (see SUMO1;
MIM 601912) is required for numerous biologic processes.
SUMO-specific proteases, such as SENP5, are responsible for the
initial processing of SUMO precursors to generate a C-terminal
diglycine motif required for the conjugation reaction. They also
have isopeptidase activity for the removal of SUMO from high
molecular mass SUMO conjugates (Di Bacco et al., 2006 [PubMed
16738315]).
Background References:
- Yun, C., et al. J. Cell Biol. 183(4):589-595(2008)
- Ding, X., et al. Oncol. Rep. 20(5):1041-1045(2008)
- Gong, L., et al. J. Biol. Chem. 281(23):15869-15877(2006)
- Di Bacco, A., et al. Mol. Cell. Biol. 26(12):4489-4498(2006)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Monkey, Mouse
Immunogen:
This SENP5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 718-747 amino acids from the C-terminal region of human SENP5.
NCBI Gene ID #:
205564
NCBI Official Name:
Sentrin-specific protease 5
NCBI Official Symbol:
SENP5
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
87 kDa
Protein Accession #:
Q96HI0
Protein GI Number:
296452962
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
Q96HI0
User NOte:
Optimal dilutions for each application to be determined by the researcher.