SERPINB11 Antibody

ProSci
Product Code: PSI-59-787
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-59-787-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in Hela cell line lysates (35ug/lane).

Western blot analysis in Hela cell line lysates (35ug/lane).

Further Information

Additional Names:
Serpin B11, SERPINB11
Application Note:
For WB starting dilution is: 1:1000
Background:
SerpinB11 is a serine proteinase inhibitor of the ovalbumin-like B clade of serpins. It was first discovered in human lung and prostate. Little is known about SerpinB11 tissue distribution and function. Splice variants of 305, 278 and 190 amino acids have been reported, with predicted masses of 33.97, 31.6 and 21.1 kDa respectively, and pIs of 8.11, 9.03 and 6.07 respectively. The 305 and 190 amino acid forms share the same aminoterminus as the 392 amino acid form. The 305 amino acid form has a deletion in residues 120-206, of the 392 amino acid form. The 190 amino acid form has a deletion in residues 57-259 relative to the long form. The 278 amino acid form starts at the third methionine, relative to the long form. All four forms contain the reactive center loop of the long form, but it is unknown if the shorter forms are active serpins. The predicted isoelectric points of SerpinB11 are significantly more basic than the other B clade serpins, and suggest a different localization or function for this serpin.
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This SERPINB11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 170-196 amino acids from the Central region of human SERPINB11.
NCBI Gene ID #:
89778
NCBI Official Name:
Serpin B11
NCBI Official Symbol:
SERPINB11
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
44 kDa
Protein Accession #:
Q96P15
Protein GI Number:
20140144
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
Q96P15
User NOte:
Optimal dilutions for each application to be determined by the researcher.