DCC1 Antibody

ProSci
Product Code: PSI-61-567
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-61-567-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Formalin-fixed and paraffin-embedded human brain tissue with DCC1 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
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Western blot analysis of DCC1 antibody in mouse heart tissue lysates (35ug/lane)

Formalin-fixed and paraffin-embedded human brain tissue with DCC1 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
Western blot analysis of DCC1 antibody in mouse heart tissue lysates (35ug/lane)

Further Information

Additional Names:
Sister chromatid cohesion protein DCC1, Defective in sister chromatid cohesion protein 1 homolog, DSCC1, DCC1
Application Note:
For IHC-P starting dilution is: 1:50~100

For WB starting dilution is: 1:1000
Background:
DCC1 is involved in sister chromatid cohesion establishment. The protein may act as a PCNA loader, loading PCNA onto primed templates.
Background References:
  • Clark H.F., Gurney A.L.Genome Res. 13:2265-2270(2003)
  • Merkle C.J., Karnitz L.M.J. Biol. Chem. 278:30051-30056(2003)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This DCC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 61-87 amino acids from the N-terminal region of human DCC1.
NCBI Gene ID #:
79075
NCBI Official Name:
Sister chromatid cohesion protein DCC1
NCBI Official Symbol:
DSCC1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
45 kDa
Protein Accession #:
Q9BVC3
Protein GI Number:
167012058
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Cell Cycle
Swissprot #:
Q9BVC3
User NOte:
Optimal dilutions for each application to be determined by the researcher.