SMC1B Antibody

ProSci
Product Code: PSI-57-308
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-57-308-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in human normal Uterus tissue lysates (35ug/lane).
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SMC1B Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human colon tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Western blot analysis in human normal Uterus tissue lysates (35ug/lane).
SMC1B Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human colon tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Further Information

Additional Names:
Structural maintenance of chromosomes protein 1B, SMC protein 1B, SMC-1-beta, SMC-1B, SMC1B, SMC1L2
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50
Background:
SMC1L2 belongs to a family of proteins required for chromatid cohesion and DNA recombination during meiosis and mitosis (3:Revenkova et al., 2001 [PubMed 11564881]).
Background References:
  • Cobbe, N., et al. Mol. Biol. Evol. 21(2):332-347(2004) Revenkova, E., et al. Mol. Cell. Biol. 21(20):6984-6998(2001) Harrington, J.J., et al. Nat. Biotechnol. 19(5):440-445(2001)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This SMC1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 737-765 amino acids from the Central region of human SMC1B.
NCBI Gene ID #:
27127
NCBI Official Name:
Structural maintenance of chromosomes protein 1B
NCBI Official Symbol:
SMC1B
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
144 kDa
Protein Accession #:
Q8NDV3
Protein GI Number:
57015410
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
Q8NDV3
User NOte:
Optimal dilutions for each application to be determined by the researcher.