TBL2 Antibody

ProSci
Product Code: PSI-56-679
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-56-679-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in ZR-75-1 cell line lysates (35ug/lane).
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TBL2 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Western blot analysis in ZR-75-1 cell line lysates (35ug/lane).
TBL2 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Further Information

Additional Names:
Transducin beta-like protein 2, WS beta-transducin repeats protein, WS-betaTRP, Williams-Beuren syndrome chromosomal region 13 protein, TBL2, WBSCR13
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50
Background:
This gene encodes a member of the beta-transducin protein family. Most proteins of the beta-transducin family are involved in regulatory functions. This protein is possibly involved in some intracellular signaling pathway. This gene is deleted in Williams-Beuren syndrome, a developmental disorder caused by deletion of multiple genes at 7q11.23.
Background References:
  • Hu, M., et al. Pharmacogenet. Genomics 20(10):634-637(2010)
  • Fontaine-Bisson, B., et al. Diabetologia 53(10):2155-2162(2010)
  • Keebler, M.E., et al. Circ Cardiovasc Genet 3(4):358-364(2010)
  • Hegele, R.A., et al. Hum. Mol. Genet. 18(21):4189-4194(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This TBL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 43-72 amino acids from the N-terminal region of human TBL2.
NCBI Gene ID #:
26608
NCBI Official Name:
Transducin beta-like protein 2
NCBI Official Symbol:
TBL2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
50 kDa
Protein Accession #:
Q9Y4P3
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
Q9Y4P3
User NOte:
Optimal dilutions for each application to be determined by the researcher.