ECT2 Antibody
| Code | Size | Price |
|---|
| PSI-57-964-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Protein ECT2, Epithelial cell-transforming sequence 2 oncogene, ECT2
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
The protein encoded by this gene is a transforming protein
that is related to Rho-specific exchange factors and yeast cell
cycle regulators. The expression of this gene is elevated with the
onset of DNA synthesis and remains elevated during G2 and M phases.
In situ hybridization analysis showed that expression is at a high
level in cells undergoing mitosis in regenerating liver. Thus, this
protein is expressed in a cell cycle-dependent manner during liver
regeneration, and is thought to have an important role in the
regulation of cytokinesis.
Background References:
- Justilien, V., et al. Oncogene 28(41):3597-3607(2009)
- Burkard, M.E., et al. PLoS Biol.(5), E1000111 (2009) :
- Wolfe, B.A., et al. PLoS Biol.(5), E1000110 (2009) :
- Hirata, D., et al. Clin. Cancer Res. 15(1):256-266(2009)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This ECT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 597-625 amino acids from the Central region of human ECT2.
NCBI Gene ID #:
1894
NCBI Official Name:
Protein ECT2
NCBI Official Symbol:
ECT2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
104 kDa
Protein Accession #:
Q9H8V3
Protein GI Number:
357529579
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
Q9H8V3
User NOte:
Optimal dilutions for each application to be determined by the researcher.