PHLDA2 Antibody
| Code | Size | Price |
|---|
| PSI-57-773-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Pleckstrin homology-like domain family A member 2, Beckwith-Wiedemann syndrome chromosomal region 1 candidate gene C protein, Imprinted in placenta and liver protein, Tumor-suppressing STF cDNA 3 protein, Tumor-suppressing subchromosomal transferable fragment candidate gene 3 protein, p17-Beckwith-Wiedemann region 1 C, p17-BWR1C, PHLDA2, BWR1C, HLDA2, IPL, TSSC3
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
This gene is located in a cluster of imprinted genes on
chromosome 11p15.5, which is considered to be an important tumor
suppressor gene region. Alterations in this region may be
associated with the Beckwith-Wiedemann syndrome, Wilms tumor,
rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and
breast cancer. This gene has been shown to be imprinted, with
preferential expression from the maternal allele in placenta and
liver.
Background References:
- O'Seaghdha, C.M., et al. Hum. Mol. Genet. 19(21):4296-4303(2010)
- Edenberg, H.J., et al. Alcohol. Clin. Exp. Res. 34(5):840-852(2010)
- Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)
- Tang, K.F., et al. Biochim. Biophys. Acta 1770(5):820-825(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PHLDA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 90-119 amino acids from the C-terminal region of human PHLDA2.
NCBI Gene ID #:
7262
NCBI Official Name:
Pleckstrin homology-like domain family A member 2
NCBI Official Symbol:
PHLDA2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
17 kDa
Protein Accession #:
Q53GA4
Protein GI Number:
84029394
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
Q53GA4
User NOte:
Optimal dilutions for each application to be determined by the researcher.