UBTD1 Antibody

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ProSci
Product Code: PSI-55-458
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-55-458-400ul400ul£626.00
Quantity:
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Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis of UBTD1 using rabbit polyclonal polyclonal antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the UBTD1 gene (Lane 2).
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Western blot analysis of in Hl60 cell line lysates (35ug/lane).
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Western blot analysis of UBTD1 using rabbit polyclonal polyclonal antibody using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the UBTD1 gene (Lane 2).
Western blot analysis of in Hl60 cell line lysates (35ug/lane).

Documents

Further Information

Additional Names:
Ubiquitin domain-containing protein 1, UBTD1
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:50
Background:
UBTD1 contains a ubiquitin domain, and has been demonstrated to bind to p53 in cells p53 is linked to the ubiquitination pathway through its transcriptional regulation of the four ubiquitin ligases, MDM2, COP1, Siah1b, and Pirh2. The role of UBTD1 has not been elucidated, however preliminary evidence indicates a potential role in p53 signaling.
Background References:
  • Ota, T., et al., Nat. Genet. 36(1):40-45 (2004).
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat
Immunogen:
This UBTD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 180-212 amino acids from the C-terminal region of human UBTD1.
NCBI Gene ID #:
80019
NCBI Official Name:
Ubiquitin domain-containing protein 1
NCBI Official Symbol:
UBTD1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
26 kDa
Protein Accession #:
Q9HAC8
Protein GI Number:
74752759
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Cell Cycle
Swissprot #:
Q9HAC8
User NOte:
Optimal dilutions for each application to be determined by the researcher.