BNIP2 Antibody

ProSci
Product Code: PSI-57-022
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-57-022-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in A549 cell line lysates (35ug/lane).
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BNIP2 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Western blot analysis in A549 cell line lysates (35ug/lane).
BNIP2 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human placenta tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Further Information

Additional Names:
BCL2/adenovirus E1B 19 kDa protein-interacting protein 2, BNIP2, NIP2
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50
Background:
This gene is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. Though the specific function is unknown, it interacts with the E1B 19 kDa protein which is responsible for the protection of virally-induced cell death, as well as E1B 19 kDa-like sequences of BCL2, also an apoptotic protector.
Background References:
  • Scott, G.B., et al. Biochem. J. 431(3):423-431(2010)
  • Shimada, M., et al. Hum. Genet. 128(4):433-441(2010)
  • Valencia, C.A., et al. Biochem. Biophys. Res. Commun. 364(3):495-501(2007)
  • Zhou, Y.T., et al. Exp. Cell Res. 303(2):263-274(2005)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This BNIP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 285-316 amino acids from the C-terminal region of human BNIP2.
NCBI Gene ID #:
663
NCBI Official Name:
BCL2/adenovirus E1B 19 kDa protein-interacting protein 2
NCBI Official Symbol:
BNIP2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
36 kDa
Protein Accession #:
Q12982
Protein GI Number:
6093506
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
Q12982
User NOte:
Optimal dilutions for each application to be determined by the researcher.