NYREN18 Antibody
| Code | Size | Price |
|---|
| PSI-61-405-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
NEDD8 ultimate buster 1, Negative regulator of ubiquitin-like proteins 1, Renal carcinoma antigen NY-REN-18, NUB1, NYREN18
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
For IHC-P starting dilution is: 1:50~100
Background:
NYREN18 is a specific down-regulator of the NEDD8 conjugation system. It recruits NEDD8 and its conjugates to the proteasome for degradation. It also interacts with PSMD4/S5a, a member of the regulatory subunit of the 26S proteasome.
Background References:
- Tanaka, T., et al., J. Biol. Chem. 278(35):32905-32913 (2003).
- Akey, D.T., et al., Hum. Mol. Genet. 11(22):2723-2733 (2002).
- Kito, K., et al., J. Biol. Chem. 276(23):20603-20609 (2001).
- Scanlan, M.J., et al., Int. J. Cancer 83(4):456-464 (1999).
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This NYREN18 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 513-542 amino acids from the C-terminal region of human NYREN18.
NCBI Gene ID #:
51667
NCBI Official Name:
NEDD8 ultimate buster 1
NCBI Official Symbol:
NUB1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
71 kDa
Protein Accession #:
Q9Y5A7
Protein GI Number:
37154888
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Cell Cycle
Swissprot #:
Q9Y5A7
User NOte:
Optimal dilutions for each application to be determined by the researcher.