LNX2 Antibody
Code | Size | Price |
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PSI-56-832-400ul | 400ul | £626.00 |
Quantity:
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Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
Ligand of Numb protein X 2, Numb-binding protein 2, PDZ domain-containing RING finger protein 1, LNX2, PDZRN1
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
LNX2 (Ligand of numb-protein X 2) is a multimodular protein that binds to NUMB via the NPXY motif. It may serve as a molecular scaffold that localizes unrelated, interacting proteins, such as NUMB, to specific subcellular sites.
Background References:
- Thorleifsson, G., et al. Nat. Genet. 41(1):18-24(2009)
- Sullivan, P.F., et al. Mol. Psychiatry 13(6):570-584(2008)
- Dunham, A., et al. Nature 428(6982):522-528(2004)
- Rice, D.S., et al. Mol. Cell. Neurosci. 18(5):525-540(2001)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This LNX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 551-579 amino acids from the C-terminal region of human LNX2.
NCBI Gene ID #:
222484
NCBI Official Name:
Ligand of Numb protein X 2
NCBI Official Symbol:
LNX2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
76 kDa
Protein Accession #:
Q8N448
Protein GI Number:
29840784
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
Q8N448
User NOte:
Optimal dilutions for each application to be determined by the researcher.