TRAIP Antibody

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ProSci
Product Code: PSI-61-527
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-61-527-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis of anti-TRAIP Antibody in HepG2 cell line lysates (35ug/lane).
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Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with TRAIP antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.
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Western blot analysis of anti-TRAIP Antibody in HepG2 cell line lysates (35ug/lane).
Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with TRAIP antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining.

Documents

Further Information

Additional Names:
E3 ubiquitin-protein ligase TRAIP, 632-, RING finger protein 206, TRAF-interacting protein, TRAIP, RNF206, TRIP
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50
Background:
TRAIP is a protein that contains an N-terminal RING finger motif and a putative coiled-coil domain. A similar murine protein interacts with TNFR-associated factor 1 (TRAF1), TNFR-associated factor 2 (TRAF2), and cylindromatosis. The interaction with TRAF2 inhibits TRAF2-mediated nuclear factor kappa-B, subunit 1 activation that is required for cell activation and protection against apoptosis.
Background References:
  • Wu,C., Proteomics(11), 1775-1785 (2007) Regamey,A., J. Exp. Med. 198 (12), 1959-1964 (2003)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This TRAIP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 328-356 amino acids from the C-terminal region of human TRAIP.
NCBI Gene ID #:
10293
NCBI Official Name:
E3 ubiquitin-protein ligase TRAIP
NCBI Official Symbol:
TRAIP
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
53 kDa
Protein Accession #:
Q9BWF2
Protein GI Number:
30580637
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Cell Cycle
Swissprot #:
Q9BWF2
User NOte:
Optimal dilutions for each application to be determined by the researcher.