FBXW12 Antibody
| Code | Size | Price |
|---|
| PSI-55-114-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Fluorescence-activated cell sorting (FACS)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
F-box/WD repeat-containing protein 12, F-box and WD-40 domain-containing protein 12, F-box only protein 35, FBXW12, FBW12, FBXO12, FBXO35
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:50~100
For FACS starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:50~100
For FACS starting dilution is: 1:10~50
Background:
Members of the F-box protein family, such as FBXW12, are
characterized by an approximately 40-amino acid F-box motif. SCF
complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM
603034), and F-box proteins, act as protein-ubiquitin ligases.
F-box proteins interact with SKP1 through the F box, and they
interact with ubiquitination targets through other protein
interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied
by OMIM].
Background References:
- Jin, J., et al. Genes Dev. 18(21):2573-2580(2004)
- Zeng, L., et al. Mol. Biol. Rep. 31(1):51-57(2004)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This FBXW12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 291-320 amino acids from the C-terminal region of human FBXW12.
NCBI Gene ID #:
285231
NCBI Official Name:
F-box/WD repeat-containing protein 12
NCBI Official Symbol:
FBXW12
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
53 kDa
Protein Accession #:
Q6X9E4
Protein GI Number:
215273983
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
Q6X9E4
User NOte:
Optimal dilutions for each application to be determined by the researcher.