GZMM Antibody

ProSci
Product Code: PSI-62-468
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-62-468-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Fluorescence-activated cell sorting (FACS)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis of GZMM Antibody in K562 cell line lysates (35ug/lane)
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GZMM Antibody IHC analysis in formalin fixed and paraffin embedded human lymph tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
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Western blot analysis of GZMM Antibody in K562 cell line lysates (35ug/lane)
GZMM Antibody IHC analysis in formalin fixed and paraffin embedded human lymph tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Further Information

Additional Names:
Granzyme M, 3421-, Met-1 serine protease, Hu-Met-1, Met-ase, Natural killer cell granular protease, GZMM, MET1
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

For FACS starting dilution is: 1:10~50
Background:
GZMM cleaves peptide substrates after methionine, leucine, and norleucine.
Background References:
  • Mahrus,S., et.al., J. Biol. Chem. 279 (52), 54275-54282 (2004)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This GZMM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 84-113 amino acids from the Central region of human GZMM.
NCBI Gene ID #:
3004
NCBI Official Name:
Granzyme M
NCBI Official Symbol:
GZMM
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
28 kDa
Protein Accession #:
P51124
Protein GI Number:
296434527
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Cell Cycle
Swissprot #:
P51124
User NOte:
Optimal dilutions for each application to be determined by the researcher.