FRK Antibody

ProSci
Product Code: PSI-63-160
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-63-160-400ul400ul£626.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Fluorescence-activated cell sorting (FACS)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis of FRK using rabbit polyclonal FRK Antibody (V28) using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the FRK gene.
2 / 3
FRK Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
3 / 3

Western blot analysis of FRK using rabbit polyclonal FRK Antibody (V28) using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the FRK gene.
FRK Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.

Further Information

Additional Names:
Tyrosine-protein kinase FRK, FYN-related kinase, Nuclear tyrosine protein kinase RAK, Protein-tyrosine kinase 5, FRK, PTK5, RAK
Application Note:
For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

For FACS starting dilution is: 1:10~50
Background:
The protein encoded by this gene belongs to the TYR family of protein kinases. This tyrosine kinase is a nuclear protein and may function during G1 and S phase of the cell cycle and suppress growth.
Background References:
  • Meyer, T., et al., Int. J. Cancer 104(2):139-146 (2003).
  • Craven, R.J., et al., Cancer Res. 55(18):3969-3972 (1995).
  • Cance, W.G., et al., Cell Growth Differ. 5(12):1347-1355 (1994).
  • Cance, W.G., et al., Int. J. Cancer 54(4):571-577 (1993).
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This FRK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 13-44 amino acids from the N-terminal region of human FRK.
NCBI Gene ID #:
2444
NCBI Official Name:
Tyrosine-protein kinase FRK
NCBI Official Symbol:
FRK
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
58 kDa
Protein Accession #:
P42685
Protein GI Number:
1169745
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Cell Cycle
Swissprot #:
P42685
User NOte:
Optimal dilutions for each application to be determined by the researcher.