PRSS7 Antibody
| Code | Size | Price |
|---|
| PSI-56-304-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Fluorescence-activated cell sorting (FACS)
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Enteropeptidase, Enterokinase, Serine protease 7, Transmembrane protease serine 15, Enteropeptidase non-catalytic heavy chain, Enteropeptidase catalytic light chain, TMPRSS15, ENTK, PRSS7
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For FACS starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
For FACS starting dilution is: 1:10~50
Background:
This gene encodes an enzyme that converts the pancreatic
proenzyme trypsinogen to trypsin, which activates other proenzymes
including chymotrypsinogen and procarboxypeptidases. The precursor
protein is cleaved into two chains that form a heterodimer linked
by a disulfide bond. This protein is a member of the trypsin family
of peptidases. Mutations in this gene cause enterokinase
deficiency, a malabsorption disorder characterized by diarrhea and
failure to thrive.
Background References:
- Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
- Nakanishi, J., et al. J. Invest. Dermatol. 130(4):944-952(2010)
- Vilen, S.T., et al. Exp. Cell Res. 314(4):914-926(2008)
- Imamura, T., et al. Am. J. Physiol. Gastrointest. Liver Physiol. 285 (6), G1235-G1241 (2003) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This PRSS7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 964-994 amino acids from the C-terminal region of human PRSS7.
NCBI Gene ID #:
5651
NCBI Official Name:
Enteropeptidase
NCBI Official Symbol:
TMPRSS15
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
113 kDa
Protein Accession #:
P98073
Protein GI Number:
317373442
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle
Swissprot #:
P98073
User NOte:
Optimal dilutions for each application to be determined by the researcher.