PCAF Antibody
| Code | Size | Price |
|---|
| PSI-56-213-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Histone acetyltransferase KAT2B, Histone acetyltransferase PCAF, Histone acetylase PCAF, Lysine acetyltransferase 2B, P300/CBP-associated factor, P/CAF, KAT2B, PCAF
Application Note:
For WB starting dilution is: 1:1000
Background:
CBP and p300 are large nuclear proteins that bind to many
sequence-specific factors involved in cell growth and/or
differentiation, including c-jun and the adenoviral oncoprotein
E1A. The protein encoded by this gene associates with p300/CBP. It
has in vitro and in vivo binding activity with CBP and p300, and
competes with E1A for binding sites in p300/CBP. It has histone
acetyl transferase activity with core histones and nucleosome core
particles, indicating that this protein plays a direct role in
transcriptional regulation.
Background References:
- Perez, R.E., et al. J. Cell. Physiol. 225(2):394-405(2010)
- Mooney, S.M., et al. J. Biol. Chem. 285(40):30443-30452(2010)
- Aoyama, T., et al. J. Biol. Chem. 285(39):29842-29850(2010)
- Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This PCAF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 802-832 amino acids from the C-terminal region of human PCAF.
NCBI Gene ID #:
8850
NCBI Official Name:
Histone acetyltransferase KAT2B
NCBI Official Symbol:
KAT2B
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
93 kDa
Protein Accession #:
Q92831
Protein GI Number:
83287776
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Research Area:
Cell Cycle,
Swissprot #:
Q92831
User NOte:
Optimal dilutions for each application to be determined by the researcher.