HERV-FRD Antibody

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ProSci
Product Code: PSI-56-798
Product Group: Primary Antibodies
Supplier: ProSci
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PSI-56-798-400ul400ul£626.00
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Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Images

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Western blot analysis in NCI-H460 cell line lysates (35ug/lane).
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Western blot analysis in NCI-H460 cell line lysates (35ug/lane).

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Further Information

Additional Names:
Syncytin-2, Endogenous retrovirus group FRD member 1, Envelope polyprotein, HERV-FRD, HERV-FRD_6p241 provirus ancestral Env polyprotein, Surface protein, SU, Transmembrane protein, TM, ERVFRD-1, ERVFRDE1
Application Note:
For WB starting dilution is: 1:1000
Background:
Human endogenous retroviruses (HERVs) make up approximately 8% of the human genome. Although most HERVs are nonfunctional, the HERV-W (ERVWE1; MIM 604659) and HERV-FRD envelope (env) proteins can induce cell-cell fusion when expressed in cells possessing appropriate receptors (Blaise et al., 2003 [PubMed 14557543]).
Background References:
  • Vargas, A., et al. J. Mol. Biol. 392(2):301-318(2009)
  • Chen, C.P., et al. Biol. Reprod. 79(5):815-823(2008)
  • Malassine, A., et al. Retrovirology 5,(2008) :
  • Mangeney, M., et al. Proc. Natl. Acad. Sci. U.S.A. 104(51):20534-20539(2007)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted species reactivity based on immunogen sequence: Monkey
Immunogen:
This HERV-FRD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 79-107 amino acids from the N-terminal region of human HERV-FRD.
NCBI Gene ID #:
405754
NCBI Official Name:
Syncytin-2
NCBI Official Symbol:
ERVFRD-1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
60 kDa
Protein Accession #:
P60508
Protein GI Number:
44887864
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,
Swissprot #:
P60508
User NOte:
Optimal dilutions for each application to be determined by the researcher.