ERV3 Antibody
| Code | Size | Price |
|---|
| PSI-57-042-400ul | 400ul | £626.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
- Immunohistochemistry- Paraffin Embedded (IHC-P)
- Western Blot (WB)
Storage:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
Endogenous retrovirus group 3 member 1 Env polyprotein, ERV-3 envelope protein, ERV3 envelope protein, ERV3-1 envelope protein, Envelope polyprotein, HERV-R envelope protein, ERV-R envelope protein, HERV-R_7q212 provirus ancestral Env polyprotein, Surface protein, SU, Transmembrane protein, TM, ERV3-1, ERV3
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Background:
The human genome includes many retroelements including the
human endogenous retroviruses (HERVs). ERV3, one of the most
studied HERVs, is thought to have integrated 30 to 40 million years
ago and is present in higher primates with the exception of
gorillas. Taken together, the observation of genome conservation,
the detection of transcript expression, and the presence of
conserved ORFs is circumstantial evidence for a functional role. A
functional role is also suggested by the observation that
downregulation of ERV3 is reported in choriocarcinoma. [provided by
RefSeq].
Background References:
- Andersson, A.C., et al. J. Virol. 79(14):9270-9284(2005)
- Herve, C.A., et al. Genomics 83(5):940-943(2004)
- Blaise, S., et al. Proc. Natl. Acad. Sci. U.S.A. 100(22):13013-13018(2003)
- de Parseval, N., et al. J. Virol. 77(19):10414-10422(2003)
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
This ERV3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 445-474 amino acids from the C-terminal region of human ERV3.
NCBI Gene ID #:
2086
NCBI Official Name:
Endogenous retrovirus group 3 member 1 Env polyprotein
NCBI Official Symbol:
ERV3-1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
68 kDa
Protein Accession #:
Q14264
Protein GI Number:
44887883
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Research Area:
Cell Cycle,
Swissprot #:
Q14264
User NOte:
Optimal dilutions for each application to be determined by the researcher.